Figure 6
![Figure 6. Effect of Unc119 G22V on CD4 T-cell proliferation. CD4 T cells were infected and sorted as in Figure 3A. Cells were then stimulated (stim.) with plastic-bound anti-CD3 and anti-CD28 Abs (3 of 28) or Concanavalin A (ConA) or left unstimulated (−) for 3 days. Cultures were pulsed with [3H] thymidine 6 hours before cell harvesting. [3H] thymidine incorporation was measured by liquid scintillation counter. N = 4 experiments using CD4 T cells from 4 different healthy donors, P < .05 (Mann-Whitney U test) was found for comparison of G22V and EV cells (*) and comparison of G22V and WT cells (#).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/119/6/10.1182_blood-2011-04-350686/5/zh89991285830006.jpeg?Expires=1722768115&Signature=3Xf6d0Z6GXFCjzLGPE4~Ltx7xj7RWybOyew89CFUuKmfQNMv3Y~BOlu6nYHVNsAcLvaoO2fOY0UNY3JEPFFYgkWkQPirJr4Tfp3SbRKAxcPBaUkpY564j~A6ka31tMIFSXbO1KuOdZypt~s9cNoANK~0~eOBg7ujktCmk-YQ3TX2HtHDWlmfpYQ-9aNRPdpgj35IwV5iu11u2O4ikAKrU2cDtsz8QIdZSUrWkRBu-qWW7E0DyRKhjWv~wnHUyGYN2VNDFQkBArmsx-DjKIxEIGi91DM1fatPOqJ6vkiSd7UWOrKlUl6-XLBmEPQvFJITwgHf667MRjxU7ZtvOn8CAg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Effect of Unc119 G22V on CD4 T-cell proliferation. CD4 T cells were infected and sorted as in Figure 3A. Cells were then stimulated (stim.) with plastic-bound anti-CD3 and anti-CD28 Abs (3 of 28) or Concanavalin A (ConA) or left unstimulated (−) for 3 days. Cultures were pulsed with [3H] thymidine 6 hours before cell harvesting. [3H] thymidine incorporation was measured by liquid scintillation counter. N = 4 experiments using CD4 T cells from 4 different healthy donors, P < .05 (Mann-Whitney U test) was found for comparison of G22V and EV cells (*) and comparison of G22V and WT cells (#).
