Structures of esterified eicosanoids acutely generated by human and murine immune cells. (A) Lipids generated by human monocytes and bronchial epithelial cells. (B) Lipids generated by human platelets and murine peritoneal macrophages. (C) Lipids generated by human macrophages. (D) Lipids generated by human neutrophils. (E-F) Lipids generated by human platelets. Note that additional lipids not shown here include esterified HpODEs generated by monocytes and macrophages, and PGE₂/D₂-PEs generated by human platelets.