Figure 3
Figure 3. Percentage of donor chimerism in granulocytes, mononuclear cells, and CD3+ in dogs treated with 211At–anti-CD45 mAb-conditioned nonmyeloablative DLA-identical bone marrow transplantation. Eight dogs received 155 to 625 μCi/kg 211At-labeled anti-CD45 mAb on day −3 followed by marrow grafts from a DLA-identical donor on day 0. The total anti-CD45 mAb dose was 0.5 mg/kg, whereof 10% was administered as unlabeled mAb 1 hour before the radioimmunoconjugate.

Percentage of donor chimerism in granulocytes, mononuclear cells, and CD3+ in dogs treated with 211At–anti-CD45 mAb-conditioned nonmyeloablative DLA-identical bone marrow transplantation. Eight dogs received 155 to 625 μCi/kg 211At-labeled anti-CD45 mAb on day −3 followed by marrow grafts from a DLA-identical donor on day 0. The total anti-CD45 mAb dose was 0.5 mg/kg, whereof 10% was administered as unlabeled mAb 1 hour before the radioimmunoconjugate.

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