Serum fluoride levels. The boxplots represent median, IQR, and the whiskers, 95% confidence intervals. Serum fluoride levels were significantly elevated in patients receiving voriconazole (median, 157 μg/L; IQR, 97 μg/L) compared with itraconazole (median < 30 μg/L; IQR, 28 μg/L), posaconazole (median < 30 μg/L, IQR, 0 μg/L), and the control group without antifungal medication (median < 30 μg/L; IQR, 28 μg/L). P < .001 for all comparisons.