Radiographic findings and bone scintigraphy in patient 2. (A) Plain film showing marked periosteal bone apposition on radial and distal diaphysis of the first metacarpal bone of the right hand (arrow). (B) Technetium 99m-methyl-diphosphonate bone scintigraphy showing marked tracer uptake in the entire skeleton, most pronounced in the spine and pelvis. There are active spots in bones of both hands and feet. (C) CT scan of the entire skeleton revealed bone appositions in various sites of the skeleton (arrows): at the caudal margin of the glenoid (top), at the dorsal ribs (middle), and periacetabular on both sides (bottom). Findings are typical of hypertrophic osteoarthropathy.