Radiographic findings and bone scintigraphy in patient 1. (A) Technetium 99m-methyl-diphosphonate bone scintigraphy showing marked tracer uptake in the entire skeleton, most pronounced in the spine and pelvis (left). There are multiple active spots in bones of both hands (right). (B) Plain film showing marked periosteal bone apposition on diaphysis of the phalanges of the left hand (arrows). Findings are typical for hypertrophic osteoarthropathy. The image was taken after 9 months of voriconazole therapy. (C) Plain film showing resolution of periosteal bone appositions on diaphysis of the phalanges (arrows). The image was taken 5 years after cessation of voriconazole therapy.