Enforced BCL2 expression inhibits the excess apoptosis of NHD13 hematopoietic progenitors. (A) Proportions of annexin-V–positive LKS cells from WT, NHD13, BCL2, and NHD13/BCL2 mice (n = 3 of each genotype). (B) Proportions of LKS cells in BM from 3 mice of each genotype. (C) CFU-GM and BFU-E numbers in BM from 3 mice of each genotype. (D) Hematocrit (HCT), red cell mean cell volume (MCV), and platelet count of 5 mice of each genotype. All measurements were made on 3-month-old mice. Error bars represent the SEM (NS indicates P > .05; *P < .05; **P < .01; ***P < .001).