Global methylation levels for all pre- and postdecitabine treatment samples. Global methylation levels were measured for each sample by the global methylation indicator (GMI; see “Global DNA methylation comparison”). The histograms represent the mean GMI values in the sample groups (n = 16). Error bars represent SD within the sample group. The P value for the pretreatment versus posttreatment comparison was calculated with a paired sample nonparametric test (Wilcoxon signed rank test).