Figure 4
Figure 4. Normal NK-mediated killing in the absence of Eri1. Lethally irradiated CD45.1+ mice were reconstituted with CD45.2+ B6 WT or Eri1−/− fetal liver cells. Ten weeks later, splenic NK cells pooled from 3-4 mice were incubated with 51Cr-labeled target (A) Ba/F3 cells or (B) Ba/F3 cells stably expressing MCMV m157. Error bars indicate SD for triplicate measurements. Data are representative of 2 independent experiments.

Normal NK-mediated killing in the absence of Eri1. Lethally irradiated CD45.1+ mice were reconstituted with CD45.2+ B6 WT or Eri1−/− fetal liver cells. Ten weeks later, splenic NK cells pooled from 3-4 mice were incubated with 51Cr-labeled target (A) Ba/F3 cells or (B) Ba/F3 cells stably expressing MCMV m157. Error bars indicate SD for triplicate measurements. Data are representative of 2 independent experiments.

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