PFS and OS among MM patients according to the copy numbers of +1q21. Kaplan-Meier analysis of PFS (A) and OS (B) is displayed in relation to no +1q21 (2 copies of 1q21; n = 233), +1q21 (3 copies; n = 95), and +1q21 (> 3 copies; n = 16) in patients treated within the HOVON-65/GMMG-HD4 trial.