Figure 6
Figure 6. Expression of BMPRIA in NK cell precursors from human lymph nodes. Lymph node mononuclear cells were used to analyze BMPRIA expression on stage 1-4 NK cell precursors. (A) Dot plot shows the expression of CD34 and CD117 in Lin− (CD3−, CD19−, CD14−, CD94−) cells. Histograms show BMPRIA expression on stage 1 CD34+ CD117− CD94−pro-NK cells, stage 2 CD34+ CD117+ CD94− pre-NK cells and stage 3 CD34− CD117+ CD94−committed immature NK cells. The percentages of positive cells are indicated in each histogram. (B) Dot plot shows the expression of CD117 and CD94 in Lin− (CD3−, CD19−, CD14−, CD34−) cells. Histograms show BMPRIA expression on stage 3 CD34− CD117+ CD94−immature NK cells and stage 4 CD34− CD117+/− CD94+ NK cells. The percentages of positive cells are indicated in each histogram. Data are representative of 3 independent experiments.

Expression of BMPRIA in NK cell precursors from human lymph nodes. Lymph node mononuclear cells were used to analyze BMPRIA expression on stage 1-4 NK cell precursors. (A) Dot plot shows the expression of CD34 and CD117 in Lin (CD3, CD19, CD14, CD94) cells. Histograms show BMPRIA expression on stage 1 CD34+ CD117 CD94pro-NK cells, stage 2 CD34+ CD117+ CD94 pre-NK cells and stage 3 CD34 CD117+ CD94committed immature NK cells. The percentages of positive cells are indicated in each histogram. (B) Dot plot shows the expression of CD117 and CD94 in Lin (CD3, CD19, CD14, CD34) cells. Histograms show BMPRIA expression on stage 3 CD34 CD117+ CD94immature NK cells and stage 4 CD34 CD117+/− CD94+ NK cells. The percentages of positive cells are indicated in each histogram. Data are representative of 3 independent experiments.

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