Global gene expression analysis in primary CCR9⁻ and CCR9⁺ pDCs isolated from murine BM. (A) Gene expression profiles of CCR9⁺ and CCR9⁻ pDCs from murine BM were analyzed by microarray and compared with signature gene sets generated from the Immgen database. Pairwise comparison of mean signal intensities of all genes of the CCR9⁻ and CCR9⁺ pDC subsets is shown. Expression of (B) CDP-specific genes and (C) pDC-specific genes was compared in CCR9⁻ and CCR9⁺ pDC subsets. Genes overexpressed > 2-fold in CCR9⁻ pDCs are shown in red; genes overexpressed > 2-fold in CCR9⁺ pDCs are indicated in green. Selected genes are highlighted by a blue circle. The percentage of differentially regulated genes among total genes is indicated.