Illustration of how the distribution of disease subsets and outcome associations would be according to the lesion found by MC. (Top) Distribution of patients detected separated according to lesion detected by metaphase cytogenetics. Patients have been grouped as follows: red, AML + high risk and intermediate-2 MDS; gray, low risk and intermediate-1 MDS; blue, hypocellular MDS; black, MDS/MPN; and green, Fanconi anemia and JMML. (Bottom) Differences in survival outcomes and progression-free survival according to MC findings. P values presented correspond to the Cox regression between the groups indicated. AML indicates acute myeloid leukemia; Chr, chromosome, MDS/MPN, myelodysplastic syndrome/myeloproliferative neoplasm; UPD, uniparental disomy; monosomy 7, deletion of whole chromosome 7; del(7q), partial deletion involving 7q; and CMML, chronic myeloid leukemia.