TIMP-3 positively correlated with IL-4 and platelet count but negatively correlated with IFN-γ in ITP patient. Plasma levels of TIMP-3 (A), IFN-γ (B), and IL-4 (C) in newly diagnosed untreated ITP patients and the healthy controls were assayed by ELISA. *P < .05; **P < .01; ***P < .001. (D-F) The correlation between plasma levels of TIMP-3 and IFN-γ or TIMP-3 and IL-4 or TIMP-3 and platelet count in ITP patients, was calculated.