Effect of scFv/TM on formation of blood clots in arterioles and venules detected using real-time in situ fluorescence microscopy. Saline (A,D), sTM (3 mg/kg; B,E), or an equimolar dose of scFv/TM (C,F) was injected in the jugular vein 1 hour before injury; N = 3 per group. Lanes indicate time-dependent platelet and fibrin accumulation at sites of arteriolar (A-C) and venular (D-F) injury. P = .0318, sTM versus scFv/TM.