Figure 4
Thromboprophylaxis by scFv/TM in venous thrombosis model in mice. Occlusion of the jugular vein was induced with FeCl3 1 hour after injection of PBS or equimolar doses of scFV/TM versus sTM, and blood flow was monitored using Doppler (supplemental Figure 4). The plot shows the data from each group presented as percentage of the preinjury blood flow in the jugular vein during the first 30 minutes after induction of thrombosis; N = 8 per group. *P = 3 × 10−10, sTM versus scFv/TM. #P = 2 × 10−10, scFv/TM versus PBS.
