The MND-huWASp LV restores B-cell development and selection. (A) Numbers of BM CD11b⁺GR1^hi neutrophils, CD11b⁺GR1^low monocytes, CD11b⁻B220⁺ B cells, and CD11b⁻CD3⁺ T cells at 40 weeks after transplant. (B) WASp expression in splenic B-cell subsets. As in Figure 2, the dotted line represents WASp expression within splenic monocytes, whereas stars identify significant deviations from monocyte marking. (C) Absolute numbers in splenic B-cell compartments. These data are from 4 independent experiments with error bars indicative of SD (n = 7 for WTM, 6 for KOM, and 19 for MND). (D) Proportion of λ⁺ cells within the splenic B-cell subsets. Error bars represent SD based on 3 unique experiments; n = 6 for WTM, 4 for KOM, and 13 for MND. Unless specifically indicated, stars indicate significant differences in WASp expression compared with splenic CD11b⁺ monocytes (*P < .05; **P < .01; ***P < .001).