Model for protein redistribution on surface of maturing erythroid cells. As EryP prepare to enucleate, redistribution of surface antigens (Ter119, orange; α4 and β1 integrins, blue) occurs such that the reticulocyte (enucleated erythroid cell) is decorated with Ter119 but displays little, if any, α4 and β1 integrin. Conversely, the extruded nucleus is preferentially coated with α4 and β1 integrins, perhaps facilitating engulfment by macrophages.⁴²  Protein redistribution has been described for maturing adult erythroblasts as well.⁵¹