In vivo thrombosis is enhanced in the absence of Jam-A. (A) Fluorescence images of cremaster muscle of Jam-A^wt/wt and Jam-A^gt/gt mice on in vivo laser-induced injury. Quantitation of peak fluorescence and the thrombus size was analyzed using Intelligent Imaging software (n = 40 injuries). (B) In vivo laser-induced injury assay as in panel A using chimeric mice generated by lethally irradiated Jam-A^wt/wt mice receiving BM transplantation from Jam-A^gt/gt mice (n = 22 injuries). Quantitation of the data analyzed using Intelligent Imaging software.