Figure 6
Figure 6. Impaired angiogenesis in skin wounded BAZF−/− mice. Eight-mm punch biopsies were made in the skin of the backs of 8 to 9-week-old BAZF+/+ or BAZF−/− mice. (A) H&E staining of wound section in BAZF+/+ and BAZF−/− mice at day 7. Scale bar: 2 mm. (B) Anti-CD31 staining of serial section in panel A. Green line: border of scab, magenta line: border of skin tissue, blue line: border of avascular area, red line: vascularized area in granulation tissue. (C) Magnified images of dot square regions in Figure 6B. Subpanels i and ii: H&E staining, iii and iv: anti-CD31 staining. Scale bar: 400 μm. Quantitative analysis of CD31+ area in whole wound area (D), CD31+ area in granulation tissue (E), and avascular area (F) in wound section of BAZF+/+ (n = 3) and BAZF−/− (n = 3) mice was carried out using ImagePro Plus 4.5.1.

Impaired angiogenesis in skin wounded BAZF−/− mice. Eight-mm punch biopsies were made in the skin of the backs of 8 to 9-week-old BAZF+/+or BAZF−/− mice. (A) H&E staining of wound section in BAZF+/+ and BAZF−/− mice at day 7. Scale bar: 2 mm. (B) Anti-CD31 staining of serial section in panel A. Green line: border of scab, magenta line: border of skin tissue, blue line: border of avascular area, red line: vascularized area in granulation tissue. (C) Magnified images of dot square regions in Figure 6B. Subpanels i and ii: H&E staining, iii and iv: anti-CD31 staining. Scale bar: 400 μm. Quantitative analysis of CD31+ area in whole wound area (D), CD31+ area in granulation tissue (E), and avascular area (F) in wound section of BAZF+/+ (n = 3) and BAZF−/− (n = 3) mice was carried out using ImagePro Plus 4.5.1.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal