Figure 3
![Figure 3. Antigen-specific T cells in single- and multipathogen-specific lines specifically proliferate upon antigen contact. Proliferation of T-cell lines specific for AdV hexon, EBV LMP2, A fumigatus p41, and/or C albicans MP65 after restimulation with the peptide pool as determined by [3H]-thymidine incorporation after 72 hours. Medians and range of at least 3 independent experiments performed in triplicate of 3 different donors are shown. Reduction of proliferative potential of multipathogen-specific lines versus single lines was only statistically significant for A fumigatus p41 (P < .001).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/118/4/10.1182_blood-2010-12-322610/4/zh89991175130003.jpeg?Expires=1722502715&Signature=pGgzWsq8Iq9keIWNlgaMhKSXPWAA0W55Zl~ew2n3zq7rEOR1-x3hMSov6QjJEUBA0UdklxCz-uUD5d40qlWC48zLe7dFxpLWh9b9B6hO813Nv8a10-lcyEqD~IHkQGfnK3ABOoK0utud8njCwFATTnF~DuKq-Q0jhFNYpJqMs29IIj697Y0jIwg-C2VQIJ7dDYvguRDAqQRBR5TNlsXMNsUIqKoJ1C33nbpPYujDbcTNz0xG0ycvddCHoEyaaKkV37vAWBJUPyLt-Y8JVng2TuG~thxARw-BoUoQ0YA8Rq-ZLWpi2GDUd6Vp6fqmGAMfY7f3-PvsrtHavHD36x-szA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Antigen-specific T cells in single- and multipathogen-specific lines specifically proliferate upon antigen contact. Proliferation of T-cell lines specific for AdV hexon, EBV LMP2, A fumigatus p41, and/or C albicans MP65 after restimulation with the peptide pool as determined by [3H]-thymidine incorporation after 72 hours. Medians and range of at least 3 independent experiments performed in triplicate of 3 different donors are shown. Reduction of proliferative potential of multipathogen-specific lines versus single lines was only statistically significant for A fumigatus p41 (P < .001).
