Risk stratification of intermediate-risk AML. The left and right panels presents Kaplan-Meier survival curve estimates for the OS and EFS in 5 AML subsets. Black lines indicate survival curves for favorable (solid line), intermediate (dashed line), and unfavorable (dotted line) cytogenetic risk subgroups of AML as defined in “Patients, cell samples, and molecular analyses.” The red curve represents the poor intermediate group defined as CD34 expression > 0.398, no IDH2 mutation, and no CEBPA^DM. The green line represents the favorable intermediate group defined as (1) CD34 expression < 0.398, (2) CD34 expression > 0.398 and CEBPA^DM, or (3) CD34 expression > 0.398, no CEBPA^DM, and IDH2 mutant.