Figure 3
Figure 3. IL-15 fails to promote CD4+ T-cell recovery in peripheral tissues despite the induction of local proliferation. (A) Percent Ki-67+ among memory (CD95+) CD4+ T cells and (B) percent of total CD4+ T cells in the lymphocyte gate in the ILN, BAL, and jejunum at pretherapy (d−13) and at d28 after therapy initiation. (C) Percent CCR5+ CD4+ memory T cells in the BAL at the same time points after therapy initiation. In panels A and C, data are expressed as in Figure 1B. In panel B, each line represents an animal.

IL-15 fails to promote CD4+ T-cell recovery in peripheral tissues despite the induction of local proliferation. (A) Percent Ki-67+ among memory (CD95+) CD4+ T cells and (B) percent of total CD4+ T cells in the lymphocyte gate in the ILN, BAL, and jejunum at pretherapy (d−13) and at d28 after therapy initiation. (C) Percent CCR5+ CD4+ memory T cells in the BAL at the same time points after therapy initiation. In panels A and C, data are expressed as in Figure 1B. In panel B, each line represents an animal.

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