Uptake of HL5B into cells as analyzed by confocal microscopy. MonoMac1 cells were pretreated for 15 minutes with Lyso-Tracker (50nM) and then incubated with IgG-FITC or HL5B-FITC conjugates (500 ng/mL each). After 7 minutes cells were imaged by confocal fluorescence microscopy under exactly identical instrument settings for all stimuli. To block cellular uptake of HL5B the aPL was coadministered with HLP (250 ng/mL), anti-FcγRII (0.5 μg/mL), or MβCD (1mM) as indicated.