Mice with deletion of CDR develop lymphoproliferations. Percentages of B-lymphoid pathologies observed in 15- to 18-month-old mice of the CDR^fl/−CD19-Cre and CDR^fl/flCD19-Cre cohorts. The percentages of MBL, CLL/small cell lymphocytic leukemia (SLL), and non-Hodgkin lymphoma (NHL) in each genotype are color coded. P values (χ² test of association) among the genotypes are indicated; n.s. indicates not significant.