Figure 4
Figure 4. Aml1-excised MLL-ENL leukemic cells revealed accelerated growth rate because of enhanced cell-cycle progression and inhibition of apoptosis. (A) Growth rate of Aml1-excised leukemic cells in liquid medium was compared with controls. Data are mean ± SD. (B-C) Cell-cycle analyses of leukemic cells by PI. (B) Representative histograms are shown. (C) Percentages of cells in S/G2/M phase (mean ± SD). (D) Percentages of apoptotic cells in each liquid medium (mean ± SD). *P < .05. We performed 3 independent experiments and confirmed that similar results were reproduced. Statistical significance was evaluated by unpaired t test.

Aml1-excised MLL-ENL leukemic cells revealed accelerated growth rate because of enhanced cell-cycle progression and inhibition of apoptosis. (A) Growth rate of Aml1-excised leukemic cells in liquid medium was compared with controls. Data are mean ± SD. (B-C) Cell-cycle analyses of leukemic cells by PI. (B) Representative histograms are shown. (C) Percentages of cells in S/G2/M phase (mean ± SD). (D) Percentages of apoptotic cells in each liquid medium (mean ± SD). *P < .05. We performed 3 independent experiments and confirmed that similar results were reproduced. Statistical significance was evaluated by unpaired t test.

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