Figure 1
dnPPARγ overexpression alters hematopoietic progenitor development. (A) FACS staining profiles of the BM progenitor populations, including LKs, LSKs, CMPs, GMPs, and MEPs from the BM of 3-month doxycycline-treated (+DOX) or untreated (−DOX) c-fms-rtTA/(tetO)7-CMV-dnPPARγ–bitransgenic mice. (B) Frequencies and total numbers of LK, LSK, CMP, MEP and GMP populations in the BM of 3-month doxycycline-treated (+DOX) or untreated (−DOX) bitransgenic mice. Values were derived from 4 mice in each group (n = 4). **P < .01.
