Normal B cell populations in mice lacking TIR8. (A-B) Dot plots of flow cytometric analysis of CD19⁺ B lineage cells to define different populations in WT and TIR8^−/− mice. Splenic marginal zone (MZ) B cells (CD21⁺CD23⁻), type 2 (T2) or mature recirculating follicular (Fo) B cells (CD21⁺ CD23⁺; A); peritoneal B1a (CD5⁺CD19⁺), B1b (CD43⁺IgM⁺) and B2 cells (CD43⁻IgM⁺; B). Data are representative of 3 animals 3 months old.