Figure 3
Inhibitory effect of ALX-0081 on ex vivo platelet adhesion to collagen type III. Representative images of platelet deposition on collagen-coated coverslips after perfusion with blood samples from healthy individuals (A) and from PCI patients receiving standard antithrombotic medication (aspirin, clopidogrel, and unfractionated heparin), incubated with buffer (B) or with ALX-0081 (C) are shown. Samples were perfused over a collagen-coated surface at a wall shear rate of 1600 s−1 and platelet adhesion was determined as percentage surface coverage. (D) Mean values ± SEM for the different treatment groups (n = 8 for each treatment group).
