Figure 4
Figure 4. Serum thrombomodulin and ANG2 levels in sensitive and refractory GVHD patients correlate with NRM. Left panels: Absolute serum levels of sTM (A-C) and ANG2 (D-F) in 23 sensitive and 25 refractory patients before stem cell transplantation (A,D), at escalation of immunosuppression (B,E), and in the follow-up period (C,F). Lines represent the medians. Mann-Whitney test was applied. Right panels: (A-C) Univariate analyses of influence on NRM comparing patients with high sTM (> 8 pg/mL, dotted lines) and patients with low sTM levels (< 8 pg/mL, thick lines). (D-F) Univariate analyses of influence on NRM comparing patients with high ANG2 (> 750 pg/mL, dotted lines) and patients with low ANG2 levels (< 750 pg/mL, thick lines).

Serum thrombomodulin and ANG2 levels in sensitive and refractory GVHD patients correlate with NRM. Left panels: Absolute serum levels of sTM (A-C) and ANG2 (D-F) in 23 sensitive and 25 refractory patients before stem cell transplantation (A,D), at escalation of immunosuppression (B,E), and in the follow-up period (C,F). Lines represent the medians. Mann-Whitney test was applied. Right panels: (A-C) Univariate analyses of influence on NRM comparing patients with high sTM (> 8 pg/mL, dotted lines) and patients with low sTM levels (< 8 pg/mL, thick lines). (D-F) Univariate analyses of influence on NRM comparing patients with high ANG2 (> 750 pg/mL, dotted lines) and patients with low ANG2 levels (< 750 pg/mL, thick lines).

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