Figure 3
Figure 3. Effect of fondaparinux, enoxaparin, or heparin on the prothrombotic activity of PCI catheter segments. Plasma was incubated with either (A) 1/1500 diluted RecombiPlasTin or (B) catheter segments, and the indicated concentrations of heparin (squares), enoxaparin (triangles), or fondaparinux (circles) for 10 minutes at 37°C. After initiating clotting by the addition of CaCl2, to 20mM, absorbance was monitored up to a maximum of 14 000 seconds, and time to clot was determined. The symbols represent the mean of ≥ 3 separate experiments, and the lines above and below the symbols reflect the SD.

Effect of fondaparinux, enoxaparin, or heparin on the prothrombotic activity of PCI catheter segments. Plasma was incubated with either (A) 1/1500 diluted RecombiPlasTin or (B) catheter segments, and the indicated concentrations of heparin (squares), enoxaparin (triangles), or fondaparinux (circles) for 10 minutes at 37°C. After initiating clotting by the addition of CaCl2, to 20mM, absorbance was monitored up to a maximum of 14 000 seconds, and time to clot was determined. The symbols represent the mean of ≥ 3 separate experiments, and the lines above and below the symbols reflect the SD.

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