American Society of Hematology

Figure 3

$Figure 3. Pre-NKP and rNKP are lineage restricted to the NK cell fate in vivo. CD45.1 unfractionated BM, CLP, pre-NKP, and rNKP were transplanted into unconditioned congenic CD45.2 Rag2−/−IL2rγc−/− recipients. Spleens 3 weeks after transplantation were isolated and analyzed by flow cytometry for lineage potential of donor cells. Each progenitor type was injected into 5 individual mice per experiment. Data are representative of 1 of 5 experiments.$

Pre-NKP and rNKP are lineage restricted to the NK cell fate in vivo. CD45.1 unfractionated BM, CLP, pre-NKP, and rNKP were transplanted into unconditioned congenic CD45.2 Rag2^−/−IL2rγc^−/− recipients. Spleens 3 weeks after transplantation were isolated and analyzed by flow cytometry for lineage potential of donor cells. Each progenitor type was injected into 5 individual mice per experiment. Data are representative of 1 of 5 experiments.

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