Pedigree of a Finnish family with multiple members affected by nodular lymphocyte predominant Hodgkin lymphoma. Multiple family members were tested for the presence of the truncating NPAT mutation and each of 4 cousins affected by the lymphoma showed this mutation (depicted as filled symbols). −/− indicates wild-type for the 2 base pair deletion in the NPAT gene and +/− indicates presence of the deletion on 1 allele. Where no genotype is indicated, no DNA was available for analysis. The pedigree has been modified for confidentiality.

Pedigree of a Finnish family with multiple members affected by nodular lymphocyte predominant Hodgkin lymphoma. Multiple family members were tested for the presence of the truncating NPAT mutation and each of 4 cousins affected by the lymphoma showed this mutation (depicted as filled symbols). −/− indicates wild-type for the 2 base pair deletion in the NPAT gene and +/− indicates presence of the deletion on 1 allele. Where no genotype is indicated, no DNA was available for analysis. The pedigree has been modified for confidentiality.

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