Effect of SGI-1776 in vivo in MV-4-11 AML xenografts. SGI-1776 was tested in MV-4-11 tumors on a daily for 5 days (qd) and twice weekly (BIW) treatment schedules. Each treatment group included 10 mice. (A) Average tumor size for the different treatment groups ± SEM. (B) Average % body weight change compared with average body weight on day 1.