Functional heterogeneity among mouse Tal1/Lmo2 T-ALLs. Leukemic cells from 7 Tal1/Lmo2 mice were transplanted through limiting dilution into syngeneic mice. Three representative Tal1/Lmo2 mouse T-ALLs are shown. Time to leukemia after transplantation of the indicated numbers of cells is shown. LIC frequency for each mouse T-ALL was calculated by applying Poisson statistics using the Limiting Dilution Version 1.1 software (StemCell Technologies).