The bivalent nanobody ALX-0081 inhibits von Willebrand factor (VWF) binding to platelet GPIbα by binding to the VWF A1 domain. VH indicates heavy chain variable domain; and Ala-Ala-Ala, alanine linker. Professional illustration by Debra T. Dartez.
The bivalent nanobody ALX-0081 inhibits von Willebrand factor (VWF) binding to platelet GPIbα by binding to the VWF A1 domain. VH indicates heavy chain variable domain; and Ala-Ala-Ala, alanine linker. Professional illustration by Debra T. Dartez.
