Panobinostat and decitabine synergize in the SCID beige DLBCL xenograft model. (A) Treatment schedules for groups of animals receiving both panobinostat and decitabine. Total decitabine dose in treatment schedule 1 was 3 mg/kg, and in treatment schedule 2 was 4.5 mg/kg. (B) Tumor volumes for treatment cohorts expressed as means. (C) Statistical significance between the groups. The upper right triangle of the table (pale gray) represents P values for actual tumor volumes between the groups; and lower left triangle (dark gray), P values for relative tumor volumes (calculated by dividing the actual volume of the tumor with its volume on the treatment day 1).