Uptake of HIV and βCD-HIV by APCs. Flow cytometric histograms (left) and whisker plots (right) showing staining for DL488 in pDCs (A), monocytes (B), and mDCs (c) from PBLs (n = 10) cultured in presence of DL488-labeled HIV or HIV treated with different concentrations of βCD (20, 80, or 120mM) and unlabeled HIV or medium alone (CTRL). In all histograms, vertical dotted lines indicate thresholds of positive staining based on unlabeled HIV control; 1 example of 10 experiments is shown. In all whisker plots, horizontal bars represent median values; vertical lines indicate interquartile range. *P values that remained significant after Hochberg correction for multiple comparisons.