Figure 1
Figure 1. Methionine residues in the A1A2A3 region of VWF. The A1A2A3 region of VWF contains 14 methionine residues, 4 each in the A1 and A3 domains and 6 in the A2 domain, including M1606 at the ADAMTS13 cleavage site. Methionine residues are the amino acids most susceptible to oxidation by HOCl.

Methionine residues in the A1A2A3 region of VWF. The A1A2A3 region of VWF contains 14 methionine residues, 4 each in the A1 and A3 domains and 6 in the A2 domain, including M1606 at the ADAMTS13 cleavage site. Methionine residues are the amino acids most susceptible to oxidation by HOCl.

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