Cumulative mean number of infections. (A) Cumulative mean number of infections in TN, R/R, and all patients. (B) Cumulative mean number of infections in patients with ≥ (dotted line) or <1.5 FC (solid line) in IgA at 12 months compared with pretreatment baseline. FC, fold change; R/R, relapsed/refactory; TN, treatment-naive.