The percentages of PD-L1⁺ malignant and nonmalignant cells within the representative tumor area in 262 DLBCL samples. (A) The percentages of PD-L1⁺ malignant cells (blue bars) and PD-L1⁺ nonmalignant cells (green bars) among the total tissue cellularity. The red line indicates the percentage of PD-L1⁺ malignant cells among all malignant cells. The cases were sorted according to the percentage of PD-L1⁺ malignant cells among the total tissue cellularity. We set the threshold for PD-L1 positivity as 30% or more of PD-L1⁺ malignant cells among the total tissue cellularity. (B) The percentages of PD-L1⁺ malignant cells (blue bars) and PD-L1⁺ nonmalignant cells (green bars) among the total tissue cellularity in PD-L1^– DLBCL samples (n = 218). The cases were sorted according to the percentage of PD-L1⁺ nonmalignant cells among the total tissue cellularity. We defined mPD-L1⁺ DLBCL as samples containing 20% or more PD-L1⁺ nonmalignant cells among the total tissue cellularity in PD-L1^– DLBCL.