A schematic relationship among the disorders that fall under the rubric of myelodysplastic neoplasms. Myelodysplastic disorders are less deviated forms of acute myelogenous leukemia.7 Here, deviation is considered in terms of loss of regulated processes of proliferation, differentiation, and maturation compared with normal polyclonal hematopoiesis. Mutational burden considers qualitative as well as quantitative oncogenetic contributions to neoplasia. Professional illustration by Patrick Lane, ScEYEnce Studios.

A schematic relationship among the disorders that fall under the rubric of myelodysplastic neoplasms. Myelodysplastic disorders are less deviated forms of acute myelogenous leukemia. Here, deviation is considered in terms of loss of regulated processes of proliferation, differentiation, and maturation compared with normal polyclonal hematopoiesis. Mutational burden considers qualitative as well as quantitative oncogenetic contributions to neoplasia. Professional illustration by Patrick Lane, ScEYEnce Studios.

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