Figure 7
Figure 7. Phenotype of rM compared with conventional DCs. (A) Levels of CD11c expression among other markers were examined on (i) naive peritoneal macrophages and (ii) rM cells compared with (iii) CD11c+ cells-FACS–sorted from a 72-hour resolving peritoneal cavity as well as (iv) GMCSF/IL-4–generated BMDCs stimulated with LPS. (B) We characterized (i) CD8+, (ii) CD8−, and (iii) plasmacytoid DCs for their (C) comparison of with rM at message level for MHC class II as well as costimulatory molecules (CD74 and CD86), monocyte-derived DCs marker (CD209a), and the immune synapse mediator Clec2i among other key rM markers summarized in Figure 3. PerC indicates peritoneal cavity. (B, see previous Figure 7A and B) We characterized (i) CD8+, (ii) CD8−, and (iii) plasmacytoid DCs for their (C) comparison of with rM at message level for MHC class II as well as costimulatory molecules (CD74 and CD86), monocyte-derived DCs marker (CD209a), and the immune synapse mediator Clec2i among other key rM markers summarized in Figure 3. PerC indicates peritoneal cavity.

Phenotype of rM compared with conventional DCs. (A) Levels of CD11c expression among other markers were examined on (i) naive peritoneal macrophages and (ii) rM cells compared with (iii) CD11c+ cells-FACS–sorted from a 72-hour resolving peritoneal cavity as well as (iv) GMCSF/IL-4–generated BMDCs stimulated with LPS. (B) We characterized (i) CD8+, (ii) CD8, and (iii) plasmacytoid DCs for their (C) comparison of with rM at message level for MHC class II as well as costimulatory molecules (CD74 and CD86), monocyte-derived DCs marker (CD209a), and the immune synapse mediator Clec2i among other key rM markers summarized in Figure 3. PerC indicates peritoneal cavity. (B, see previous Figure 7A and B) We characterized (i) CD8+, (ii) CD8, and (iii) plasmacytoid DCs for their (C) comparison of with rM at message level for MHC class II as well as costimulatory molecules (CD74 and CD86), monocyte-derived DCs marker (CD209a), and the immune synapse mediator Clec2i among other key rM markers summarized in Figure 3. PerC indicates peritoneal cavity.

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