Unique phenotype of rM. Authors' interpretation of key pathways defining rM are highlighted in color. For example, gold represents those genes central to antigen uptake and processing (all other genes in this pathway are in white and not enriched in rM); and green, chemokines and their receptors expressed/secreted by rM that trigger T-/B-cell chemoattraction or that which facilitate lymphocyte expansion/differentiation or T-cell/rM interaction, such as Clec2i, TNFsf4/OX, and XCL1.