Inactivation of Trp53 rescues the Rps19-deficient hematopoiesis depending on the level of Rps19 down-regulation. Lethally irradiated wild-type recipient mice were transplanted with 5 × 10⁶ bone marrow cells from transgenic donors (that were either Trp53^+/+, Trp53^+/−, or Trp53^−/−) followed by doxycycline administration to recipients starting 2 weeks after transplantation. Erythrocyte, platelet, and leukocyte numbers in peripheral blood of recipient mice after 2 weeks of doxycycline administration are shown (n = 4-9 recipients per genotype). Error bars represent SD.