Deformability of cRBCs studied by LORCA. Deformability of cRBCs was studied by LORCA. The deformability profile of day 18 cRBCs (n = 2, red curves) was compared with those of (1) mature peripheral RBCs from healthy donors (native RBC) as the control (n = 10, black circles) and (2) native reticulocytes (n = 3, gray crosses). The EI at 3 and 30 Pa is given in the table for each group and results are expressed as the mean ± SEM.