Effects of PRT318 on SYK phosphorylation in sensitive and resistant DLBCL cells. (A) Confocal images of sensitive LY7 cells treated with or without various concentrations of PRT318 as indicated on the left of the images. Proteins labeled are indicated at the top of the images. Merged and bright-field images are also shown. (B) Confocal images of resistant LY3 cells treated with or without various concentrations of PRT318, as indicated on the left of the images. Molecules labeled are indicated on top of the images. Merged and bright-field images are also shown.