NUP98/NSD1 confers a poor outcome in pediatric and adult AML. Survival curves of the pediatric cohort (n = 238; A-C) and adult cohort (n = 727; D-F) depicting the cumulative incidence of nonresponse/relapse (CIR) according to the Kalbfleisch and Prentice method (A,D) and Kaplan-Meier estimates of pEFS (B,E) and pOS (C,F).