NUP98/NSD1 is a frequent event in pediatric CN-AML. (A) Pie charts showing percentage of the different type-II aberrations found in pediatric CN-AML (n = 62; left pie chart) and in adult CN-AML (n = 344; right pie chart). The mutational analysis of CEBPA and MLL was not available for the adult cohort. (B) Histogram representing the percentage of the NUP98/NSD1 positive cases within the different age categories in CN-AML shows a decreasing frequency of NUP98/NSD1 with age.