OS in patients with HIV-associated MCD. Kaplan-Meier survival statistics were used to evaluate OS in all 52 patients with HIV-MCD (A) and in those 47 patients who received treatment for HIV-MCD (B). OS was defined as the period from HIV-MCD diagnosis to death from any cause or the last contact (which was censored). During the study period (1998-2010), OS improved markedly since 2006. The mean estimated OS in the years 1998 to 2005 was 1.5 years versus not reached in the years 2006 to 2010 (P = .0035, panel A). When only patients receiving at least 1 HIV-MCD treatment were included, there was only a trend (P = .24) toward a better OS during recent years (panel B).